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How We Grade Evidence

Transparency is core to Peptide Atlas. Here's exactly how we evaluate and rate the evidence behind each peptide.

Every peptide in our database is assigned an evidence level and a safety rating. These are not marketing claims — they reflect our honest assessment of the available scientific literature. We use a structured framework that considers human clinical trials, animal studies, mechanistic research, and expert consensus.

Evidence Levels

Strong90%

Supported by multiple human clinical trials

Moderate70%

Some human data with consistent preclinical support

Emerging50%

Early human data or strong animal evidence

Preliminary30%

Mostly preclinical with limited human data

Limited15%

Very early research, mostly mechanistic

Safety Ratings

Well-Studied

Extensive safety data available

Moderate Data

Some safety data, generally well-tolerated

Limited Data

Limited safety data, discuss with clinician

Use Caution

Notable risks or very limited safety data

Our Methodology

1. Literature Review

We review published peer-reviewed studies, including randomized controlled trials, cohort studies, case reports, and systematic reviews from PubMed, Google Scholar, and specialty journals.

2. Evidence Hierarchy

We weight evidence based on study quality: large RCTs carry more weight than animal studies or anecdotal reports. We note when evidence comes primarily from preclinical research.

3. Clinician Review

All content is reviewed by board-certified clinicians with experience in peptide therapy. They verify accuracy, flag misleading claims, and add clinical context.

4. Ongoing Updates

Evidence levels are not static. As new research emerges, we update our ratings. Each peptide page shows when it was last reviewed.

Important Note

Our evidence ratings represent our best assessment of the current scientific literature. They are not FDA evaluations or medical recommendations. Individual responses to peptides vary, and all decisions about peptide therapy should be made in consultation with a qualified healthcare provider.