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Peptide Directory

Explore all 73 peptides with evidence ratings, safety profiles, and research-backed content.

73 peptides found

BPC-157

Gastric Peptide

Beginner

A synthetic peptide derived from a protective protein found in gastric juice, widely discussed for tissue repair and recovery.

RecoveryGut HealthTissue Repair+2
EmergingModerate Data

Semaglutide

GLP-1 Receptor Agonist

Beginner

A GLP-1 receptor agonist FDA-approved for type 2 diabetes and chronic weight management, one of the most widely prescribed peptide drugs.

Weight LossMetabolic HealthFDA-Approved+1
StrongWell-Studied

Tirzepatide

Dual GIP/GLP-1 Receptor Agonist

Beginner

A dual GIP/GLP-1 receptor agonist FDA-approved for diabetes and weight management, producing the largest weight loss seen in clinical trials.

Weight LossMetabolic HealthFDA-Approved+2
StrongWell-Studied

CJC-1295

GHRH Analog

Beginner

A growth hormone-releasing hormone analog that stimulates the pituitary gland to produce more growth hormone.

Growth HormoneBody CompositionRecovery+2
ModerateModerate Data

Ipamorelin

Growth Hormone Secretagogue

Beginner

A selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol or prolactin.

Growth HormoneBody CompositionRecovery+2
ModerateModerate Data

NAD+ Precursors (NMN/NR)

Nucleotide/Vitamin B3 Derivative

Beginner

Precursors to NAD+, a critical coenzyme for cellular energy and longevity pathways. NAD+ levels decline with age.

LongevityAnti-AgingCellular Energy+1
ModerateWell-Studied

TB-500

Tissue Repair Peptide

Beginner

A synthetic version of the active region of thymosin beta-4, widely used for tissue repair, wound healing, and recovery from injuries.

RecoveryWound HealingAnti-Inflammatory+1
EmergingModerate Data

GHK-Cu

Copper Peptide

Beginner

A naturally occurring copper-binding peptide with extensive research on skin remodeling, wound healing, and anti-aging.

SkinAnti-AgingWound Healing+2
ModerateWell-Studied

Retatrutide

Triple GIP/GLP-1/Glucagon Receptor Agonist

An investigational triple agonist (GIP/GLP-1/glucagon) that produced 24% weight loss in Phase II trials, potentially the most effective obesity drug.

Weight LossInvestigationalGLP-1+2
EmergingModerate Data

Oxytocin

Neuropeptide Hormone

Beginner

A naturally occurring neuropeptide involved in social bonding, trust, and reproduction, FDA-approved for labor induction.

HormonalFDA-ApprovedSocial Bonding+1
StrongWell-Studied

Glutathione

Tripeptide Antioxidant

Beginner

The body's most abundant antioxidant, a tripeptide critical for detoxification, immune function, and cellular protection.

AntioxidantDetoxificationImmune+2
ModerateWell-Studied

Semax

Nootropic Peptide

Beginner

A synthetic peptide analog of ACTH(4-10) developed in Russia, studied for cognitive enhancement and neuroprotection.

Cognitive SupportNeuroprotectionFocus+1
EmergingModerate Data

Sermorelin

GHRH Analog

Beginner

A growth hormone-releasing hormone analog that was previously FDA-approved for diagnosing GH deficiency in children.

Growth HormoneAnti-AgingSleep+1
StrongWell-Studied

MK-677

Growth Hormone Secretagogue

An orally active growth hormone secretagogue that mimics ghrelin to stimulate GH and IGF-1 release.

Growth HormoneBody CompositionSleep+2
ModerateModerate Data

PT-141 (Bremelanotide)

Melanocortin Receptor Agonist

Beginner

An FDA-approved melanocortin receptor agonist for hypoactive sexual desire disorder in premenopausal women, also studied for broader sexual dysfunction.

Sexual WellnessFDA-ApprovedLibido+1
StrongWell-Studied

BPC-157 Arginate

Gastric Peptide

Beginner

A stabilized form of BPC-157 combined with arginine, offering enhanced stability and potentially improved oral bioavailability.

RecoveryGut HealthTissue Repair+2
PreliminaryLimited Data

CJC-1295 (no DAC)

GHRH Analog

Beginner

A modified growth hormone releasing hormone analog with a shorter half-life than DAC-conjugated CJC-1295, allowing more physiological GH pulsing.

Growth HormoneBody CompositionRecovery+1
ModerateModerate Data

Liraglutide

GLP-1 Receptor Agonist

Beginner

A GLP-1 receptor agonist FDA-approved for diabetes (Victoza) and weight management (Saxenda), the predecessor to semaglutide.

Weight LossMetabolic HealthFDA-Approved+1
StrongWell-Studied

Follistatin

Activin-Binding Protein

A naturally occurring protein that inhibits myostatin (the muscle growth limiter), studied for dramatic muscle growth potential.

Muscle GrowthMyostatin InhibitorPerformance
EmergingLimited Data

KPV

Anti-Inflammatory Tripeptide

Beginner

A tripeptide fragment of alpha-MSH with potent anti-inflammatory properties, studied for inflammatory bowel disease and skin conditions.

Anti-InflammatoryGut HealthSkin Health+1
EmergingLimited Data

Argireline

Cosmetic Peptide

Beginner

A cosmetic peptide that reduces wrinkles by inhibiting neurotransmitter release at the neuromuscular junction, often called 'topical Botox.'

Skin HealthAnti-AgingTopical+1
ModerateWell-Studied

Matrixyl

Signal Peptide (Cosmetic)

Beginner

A collagen-stimulating cosmetic peptide that signals skin to produce more collagen and extracellular matrix proteins.

Skin HealthAnti-AgingCollagen+1
ModerateWell-Studied

Cagrilintide

Amylin Analogue

A long-acting amylin analogue being developed in combination with semaglutide (CagriSema) for enhanced weight loss.

Weight LossMetabolic HealthInvestigational
EmergingModerate Data

Selank

Nootropic Peptide

Beginner

A synthetic peptide analog of tuftsin with anxiolytic and nootropic properties, developed in Russia.

AnxietyMoodCognitive Support+1
EmergingModerate Data

Tesamorelin

GHRH Analog

An FDA-approved GHRH analog used to reduce visceral fat in HIV-associated lipodystrophy.

Growth HormoneBody CompositionFat Loss+1
StrongWell-Studied

AOD-9604

GH Fragment

Beginner

A modified fragment of human growth hormone studied specifically for fat metabolism without the growth-promoting effects of full GH.

Fat LossBody CompositionMetabolic
EmergingModerate Data

FOXO4-DRI

Senolytic Peptide

A senolytic peptide designed to selectively clear senescent cells by disrupting the FOXO4-p53 interaction, studied for anti-aging applications.

LongevitySenolyticAnti-Aging+1
PreliminaryLimited Data

Cerebrolysin

Neurotrophic Peptide Complex

A porcine brain-derived peptide preparation with neurotrophic properties, approved in several countries for stroke recovery and cognitive disorders.

NeuroprotectionCognitive EnhancementStroke Recovery+1
StrongWell-Studied

GHR-2 (GHRP-2)

Growth Hormone Secretagogue

A synthetic growth hormone secretagogue that stimulates natural GH release, studied for body composition, recovery, and anti-aging.

Growth HormoneBody CompositionRecovery+1
ModerateModerate Data

Hexarelin

Growth Hormone Secretagogue

A potent growth hormone secretagogue peptide that also has cardioprotective properties independent of GH release.

Growth HormoneCardioprotectiveNeuroprotective+1
ModerateModerate Data

IGF-1 LR3

Growth Factor Analogue

A modified version of IGF-1 with extended half-life and reduced IGF binding protein affinity, used for muscle growth.

Growth FactorMuscle GrowthPerformance
EmergingLimited Data

N-Acetyl Selank Amidate

Nootropic Peptide

Beginner

An enhanced version of Selank with improved stability, studied for anxiety reduction and cognitive enhancement.

CognitiveAnxiolyticNootropic+1
EmergingModerate Data

Gonadorelin

Gonadotropin-Releasing Hormone

Synthetic gonadotropin-releasing hormone used diagnostically and therapeutically for reproductive hormone assessment and fertility.

HormonalFertilityDiagnostic+1
StrongWell-Studied

Melanotan II

Melanocortin Agonist

A synthetic melanocortin peptide studied for tanning, sexual function, and appetite suppression. Not FDA-approved; the FDA has issued public warnings against its use.

SkinSexual WellnessAppetite+1
EmergingUse Caution

Epithalon

Bioregulator Peptide

A synthetic tetrapeptide studied for its potential to activate telomerase and influence cellular aging.

LongevityAnti-AgingTelomeres+1
PreliminaryLimited Data

Thymosin Alpha-1

Thymic Peptide

A thymic peptide approved in multiple countries for immune modulation, particularly in hepatitis and as a vaccine adjuvant.

Immune SupportApproved InternationallyHepatitis+1
StrongWell-Studied

Humanin

Mitochondrial-Derived Peptide

A mitochondria-derived peptide with cytoprotective properties, studied for neuroprotection, metabolic regulation, and anti-aging effects.

NeuroprotectionLongevityMetabolic Health+1
EmergingLimited Data

VIP

Neuropeptide

A naturally occurring neuropeptide with anti-inflammatory, neuroprotective, and immune-modulating properties. Early clinical data exists for pulmonary hypertension; other therapeutic uses remain under investigation.

Anti-InflammatoryNeuroprotectionImmune Modulation+1
ModerateModerate Data

GHRP-6

Growth Hormone Secretagogue

A synthetic growth hormone secretagogue known for potent GH release and significant appetite stimulation through ghrelin receptor activation.

Growth HormoneAppetiteBody Composition+1
ModerateModerate Data

Larazotide

Tight Junction Regulator

Beginner

A synthetic peptide that regulates intestinal tight junctions, in clinical trials for celiac disease and studied for leaky gut conditions.

Gut HealthTight JunctionsCeliac Disease+1
ModerateWell-Studied

Exenatide

GLP-1 Receptor Agonist

Beginner

The first GLP-1 receptor agonist, originally derived from Gila monster venom, FDA-approved for type 2 diabetes.

Metabolic HealthFDA-ApprovedGLP-1
StrongWell-Studied

IGF-1 DES

Growth Factor Analogue

A truncated form of IGF-1 missing the first 3 amino acids, with 10x greater potency and very short half-life for localized effects.

Growth FactorMuscle GrowthPerformance
EmergingLimited Data

MGF

Growth Factor Splice Variant

A splice variant of IGF-1 produced in response to mechanical stress on muscles, promoting satellite cell activation and muscle repair.

Growth FactorMuscle GrowthRecovery
EmergingLimited Data

PEG-MGF

PEGylated Growth Factor

A PEGylated version of MGF with extended half-life for systemic muscle growth and recovery effects.

Growth FactorMuscle GrowthRecovery
PreliminaryLimited Data

Teriparatide

Parathyroid Hormone Fragment

An FDA-approved fragment of parathyroid hormone that stimulates new bone formation, used for severe osteoporosis.

Bone HealthFDA-ApprovedHormonal
StrongWell-Studied

Orexin-A

Neuropeptide

A neuropeptide that regulates wakefulness, arousal, and appetite. Its deficiency causes narcolepsy.

SleepCognitiveWakefulness+1
EmergingLimited Data

P21

Neurotrophic Peptide

A CNTF-derived peptide that promotes neurogenesis and has shown promise in Alzheimer's disease research.

CognitiveNeuroprotectiveNeurogenesis
PreliminaryLimited Data

Leuprolide

GnRH Agonist

An FDA-approved GnRH agonist used for prostate cancer, endometriosis, and precocious puberty through hormonal suppression.

FDA-ApprovedHormonalOncology+1
StrongWell-Studied

Glucagon

Peptide Hormone

Beginner

A naturally occurring peptide hormone that raises blood sugar, FDA-approved as emergency treatment for severe hypoglycemia.

FDA-ApprovedMetabolic HealthEmergency Medicine
StrongWell-Studied

N-Acetyl Epithalon Amidate

Bioregulator Peptide

An enhanced version of Epithalon with improved stability, studied for telomerase activation, pineal gland regulation, and anti-aging effects.

LongevityAnti-AgingTelomeres+2
PreliminaryLimited Data

LL-37

Antimicrobial Peptide

A naturally occurring antimicrobial peptide that plays a key role in innate immune defense.

Immune SupportAntimicrobialGut Health+1
EmergingLimited Data

Dihexa

Angiotensin Analog

A potent angiotensin IV analog studied for cognitive enhancement and potential treatment of neurodegenerative conditions.

Cognitive SupportNeuroprotectionMemory+1
PreliminaryLimited Data

DSIP

Neuropeptide

A naturally occurring neuropeptide that modulates sleep patterns and has been studied for insomnia and stress.

SleepStressMood+1
EmergingLimited Data

SNAP-8

Cosmetic Peptide

Beginner

A cosmetic peptide that reduces the appearance of wrinkles by modulating neuromuscular junction signaling.

SkinAnti-AgingWrinkles+2
EmergingWell-Studied

MOTS-c

Mitochondrial Peptide

A mitochondria-derived peptide that regulates metabolic homeostasis and has been called an 'exercise mimetic.'

MetabolicExerciseLongevity+1
EmergingLimited Data

Thymalin

Thymic Peptide

A thymic peptide complex studied for immune system restoration, particularly in aging populations and immunocompromised states.

Immune SupportLongevityAnti-Aging+1
ModerateModerate Data

PE-22-28

Neuroactive Peptide

A synthetic peptide derived from sortilin that acts as a TREK-1 channel blocker, studied as a rapid-acting antidepressant alternative.

MoodAntidepressantNeuroplasticity+1
PreliminaryLimited Data

Calcitonin (Salmon)

Peptide Hormone

Beginner

An FDA-approved peptide hormone used to treat osteoporosis and Paget's disease by inhibiting bone resorption.

Bone HealthFDA-ApprovedHormonal
StrongWell-Studied

Desmopressin

Vasopressin Analogue

Beginner

A synthetic analogue of vasopressin (ADH) FDA-approved for diabetes insipidus, bedwetting, and bleeding disorders.

HormonalFDA-ApprovedKidney
StrongWell-Studied

Pramlintide

Amylin Analogue

An FDA-approved synthetic analogue of amylin used alongside insulin for diabetes, also studied for weight management.

Metabolic HealthFDA-ApprovedWeight Loss+1
StrongWell-Studied

Setmelanotide

Melanocortin-4 Receptor Agonist

An FDA-approved MC4R agonist for rare genetic obesity disorders, representing a precision medicine approach to weight management.

Weight LossFDA-ApprovedGenetic Obesity+1
StrongWell-Studied

Octreotide

Somatostatin Analogue

An FDA-approved somatostatin analogue used to treat acromegaly, carcinoid tumors, and severe diarrhea.

FDA-ApprovedHormonalOncology
StrongWell-Studied

Glatiramer Acetate

Immunomodulatory Peptide Mixture

An FDA-approved immunomodulatory peptide mixture for relapsing-remitting multiple sclerosis (MS).

FDA-ApprovedImmuneAutoimmune+1
StrongWell-Studied

Pentosan Polysulfate

Polysaccharide

A semi-synthetic polysaccharide with FDA approval for interstitial cystitis, also studied for joint and cartilage health.

Joint HealthFDA-ApprovedCartilage+1
StrongWell-Studied

NA-Semax-Amidate

Nootropic Peptide

A chemically modified version of Semax designed for improved stability. No published clinical or preclinical data exists for this specific compound.

Cognitive SupportNeuroprotectionFocus+1
LimitedLimited Data

Kisspeptin

Neuropeptide

A naturally occurring neuropeptide that plays a central role in reproductive hormone regulation and fertility.

HormonalFertilityReproductive Health+1
ModerateModerate Data

SS-31

Mitochondrial Peptide

A mitochondria-targeted peptide in clinical trials for heart failure and mitochondrial diseases.

MitochondrialHeart HealthLongevity+1
EmergingModerate Data

Pinealon

Bioregulator Peptide

Beginner

A short tripeptide studied for neuroprotective and cognitive-enhancing properties, part of the Khavinson peptide bioregulator family.

NeuroprotectionCognitive EnhancementAnti-Aging+1
PreliminaryLimited Data

Thymulin

Thymic Peptide

A zinc-dependent thymic peptide involved in T-cell maturation, studied for immune restoration and anti-inflammatory applications.

Immune SupportAnti-InflammatoryThymic+1
EmergingModerate Data

Cortagen

Bioregulator Peptide

A synthetic peptide bioregulator targeting brain cortex function, studied for cognitive enhancement and neuroprotection in aging.

Cognitive EnhancementNeuroprotectionBioregulator+1
PreliminaryLimited Data

Difelikefalin

Peripheral Kappa Opioid Agonist

An FDA-approved peripheral kappa opioid receptor agonist for chronic kidney disease-associated itch, without CNS side effects.

FDA-ApprovedPainKidney+1
StrongWell-Studied

Teduglutide

GLP-2 Analogue

An FDA-approved GLP-2 analogue that promotes intestinal growth, used for short bowel syndrome.

FDA-ApprovedGut HealthIntestinal Growth
StrongWell-Studied

Trofinetide

IGF-1 Tripeptide Analogue

The first FDA-approved treatment for Rett syndrome, a synthetic analogue of a naturally occurring IGF-1 tripeptide fragment.

FDA-ApprovedNeuroprotectiveRare Disease
StrongWell-Studied