IGF-1 LR3

The role of the insulin-like growth factor 1 (IGF-1) in skeletal muscle physiology

Type I insulin-like growth factor receptor signaling in skeletal muscle regeneration and hypertrophy

IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep

Revolutionary decellularized Alstroemeria stem-based nerve conduit integrated with GelMA and controlled IGF-1 LR3 release for enhanced rat sciatic nerve regeneration

Attenuated glucose-stimulated insulin secretion during an acute IGF-1 LR3 infusion into fetal sheep does not persist in isolated islets

Impaired muscle regeneration and myoblast differentiation in mice with a muscle-specific KO of IGF-IR

Anabolic effects of insulin-like growth factor-I (IGF-I) and an IGF-I variant in normal female rats.

IGF-I variants which bind poorly to IGF-binding proteins show more potent and prolonged hypoglycaemic action than native IGF-I in pigs and marmoset monkeys.

Superior potency of infused IGF-I analogues which bind poorly to IGF-binding proteins is maintained when administered by injection.

Insulin-like growth factor-I and more potent variants restore growth of diabetic rats without inducing all characteristic insulin effects.

Long [R3] insulin-like growth factor-I reduces growth, plasma growth hormone, IGF binding protein-3 and endogenous IGF-I concentrations in pigs.

Prolonged administration of IGF peptides enhances growth of gastrointestinal tissues in normal rats.

Treatment with IGF-I peptides improves function of the remnant gut following small bowel resection in rats.

Preferential intestinal delivery of long[Arg3] insulin-like growth factor (LR3IGF-I) over IGF-I in preweaning and adult rats.

Transport of circulating IGF-I and LR3IGF-I from blood to extracellular wound fluid sites in rats.

Effects of insulin-like growth factor-I and LR3IGF-I on regional blood flow in normal rats.

The role of insulin-like growth factors in small intestinal cell growth and development.

Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.

Insulin-like growth factor-I and analogues increase growth in artificially-reared neonatal pigs.

Effects of chronic renal failure on plasma clearance of insulin-like growth factor I, des-(1-3)IGF-I, and LR3IGF-I.