N-Acetyl Selank Amidate
An enhanced version of Selank with improved stability, studied for anxiety reduction and cognitive enhancement.
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This information is for educational purposes. Peptide therapy should be guided by a licensed healthcare provider. Connect with a Noho clinician
What is N-Acetyl Selank Amidate?
N-Acetyl Selank Amidate is a modified version of Selank with N-acetyl and C-amide terminal modifications that improve enzymatic stability and nasal absorption. Like standard Selank, it is a synthetic analogue of the naturally occurring immunopeptide tuftsin, with anxiolytic and nootropic properties.
Why People Talk About It
Enhanced anxiety reduction vs standard Selank
EmergingImproved cognitive function and focus
EmergingBetter stability and bioavailability
ModerateHow It Works
This is a more stable version of Selank that helps reduce anxiety and improve mental clarity. It works by modulating GABA (the brain's calming neurotransmitter) and BDNF (a brain growth factor) without causing sedation or dependence.
Common Questions
Safety Information
Common Side Effects
Cautions
- • Not FDA-approved
- • Limited data specific to the modified form
- • May interact with GABAergic medications
What We Don't Know
Safety data specific to the N-acetyl amidate form is limited. Extrapolated from Selank data.
Published Research
14 studies[Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia]
SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts
Hyperbaric hyperoxia alters innate immune functional properties during NASA Extreme Environment Mission Operation (NEEMO)
Sleep research in space: expression of immediate early genes in forebrain structures of rats during the nasa neurolab mission (STS-90)
Characterization of the osteoblast-like cell phenotype under microgravity conditions in the NASA-approved Rotating Wall Vessel bioreactor (RWV)
Physical and biological studies with protons and HZE particles in a NASA supported research center in radiation health
Erythroid cell growth and differentiation in vitro in the simulated microgravity environment of the NASA rotating wall vessel bioreactor
Biological Macromolecule Crystallization Database, Version 3.0: new features, data and the NASA archive for protein crystal growth data
Delivery of recombinant human growth hormone to rats during exposure to microgravity on NASA Space Shuttle Discovery
Atriopeptin (AP-3) in atria and plasma of rats orbited aboard NASA Spacelab (SL3) for seven days
EXPERIMENTAL INVESTIGATIONS ON ULTRA-LOW FREQUENCY DISPLACEMENT BALLISTOCARDIOGRAPHY. NASA TT F-269
A critical study of the absorption of polypeptides in the far-ultraviolet as a means of extraterrestrial life detection. NASA TM X-1131
Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission
Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats
Always consult a qualified clinician
This information is for educational purposes. Peptide therapy should be guided by a licensed healthcare provider. Connect with a Noho clinician
Research Insights
Related Peptides
Selank
EmergingBeginnerA synthetic peptide analog of tuftsin with anxiolytic and nootropic properties, developed in Russia.
Semax
EmergingBeginnerA synthetic peptide analog of ACTH(4-10) developed in Russia, studied for cognitive enhancement and neuroprotection.
NA-Semax-Amidate
LimitedA chemically modified version of Semax designed for improved stability. No published clinical or preclinical data exists for this specific compound.
Quick Facts
- Class
- Nootropic Peptide
- Evidence
- Emerging
- Safety
- Moderate Data
- Updated
- Mar 2026
- Citations
- 14PubMed
Also known as
Tags
Related Goals
Evidence Score
Clinical Trials
View Clinical TrialsLinks to ClinicalTrials.gov for reference. Listing does not imply endorsement.
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